Metchkinikoff (1899) at Metelnikoff (1890) ay nakakita na ang spermatozoa ay may antigenic property at maaaring magpalabas ng specific antibody, na nagbukas ng bagong panahon sa reproductive immunology. Noong dekada 1950, si Wilson at Rumre ay nakakita ng anti-sperm antibody (ASAB) sa dugo ng mga lalaking may infertility, na nagpaunlad ng interes ng mga doktor sa immune infertility. Bagaman ang mga pananaliksik ay naging malawak sa bansa at sa buong mundo, at mayroong ilang progreso, ang male immune infertility ay patuloy na isang mahirap na kaso sa urology. Ang author ay nakakita ng resulta sa pamamagitan ng paggamit ng diagnosis at treatment principles sa loob ng ilang taon. Narito ang apat na pangunahing paraan.
1. Pamahalaan ang Liver at Kidney, Bawasan ang Blood at Qi, Bigyan ng suporta sa pagbubuo ng sperm. Ang lalaki ay nakabase sa sperm, at ang qi ang gamit. Kung ang sperm at blood ay sapat, ang organs ay aktibo at hindi madaling maapektuhan ng mga external pathogens. Ngayon, ang liver at kidney ay nawalan ng sperm at blood, ang qi at blood ay hindi balanced, ang sperm chamber ay walang nilalaman, at nadagdagan ng mga pathogen, na nagdudulot ng antibody. Ang mga pasyente na may ganitong kondisyon ay madalas may history ng excessive sex, high libido, injury o infection sa reproductive organ. Ang sintomas ay afternoon fever, heat in palms, soles, and chest, thirst, low back pain, weak knees, yellow urine, constipation, night sweats, red tongue with little coating, fine wiry pulse. Ang pangangasiwa ay dapat supplement ang liver at kidney. Gamitin ang Zuan Yin Shengjing 1st Formula (self-made): 10 grams each of raw rehmannia, cooked rehmannia, alisma, moutan bark, cornus, goji berry, polygonatum, chinese yam, anemarrhena, and poria; 30 grams each of raw softshell turtle shell (pre-boiled) and raw oyster shell (pre-boiled); 15 grams each of dried peach kernel and Baidu San (wrapped). Inumin nang isang beses araw-araw.
Halimbawa 1: Zhang, lalaki, 33 taon. Unang pagbisita noong Setyembre 6, 1994. Sinabi niyang 3 taon na walang anak, mag-asawa na, normal ang sex life. Ang babae ay walang anomalya. Ang sperm test ay normal, ang serum ASAB (+). Kasalukuyang estado: malungkot, dizziness, blurred vision, occasional tinnitus, thirsty, low back and knee weakness, yellow urine, red tongue with little coating, fine rapid pulse. Diagnosis: liver and kidney yin deficiency, internal fire. Pangangasiwa: nourish yin, reduce fire, gamitin ang Zuan Yin Shengjing 1st Formula na may pagbabago. Pagkatapos ng 4 buwan, ang sperm test at serum ASAB ay pareho normal, ginamit ang therapy para sa 2 buwan, ang asawa ay nagbuntis.
2. Pamahalaan ang Spleen at Kidney, Bigyan ng suporta sa digestive system, bawasan ang qi, at bigyan ng protection. Bagamat ang sakit ay nasa kidney, ang pangunahing dahilan ay ang kidney deficiency, ngunit ang congenital kidney essence ay depende sa posterior spleen and stomach for nourishment from food and water. At "the spleen disperses essence, which goes upward to the lung." The lung's qi and yin come from spleen and kidney. The lung's defensive qi can nourish the whole body, moisturize the skin, resist pathogens, enhance immunity, and serve as the body’s outer barrier. The strength of defensive qi is closely related to the coordination of immune function. When spleen and lung qi are weak, abnormal antibodies are produced. Ang mga pasyente na may ganitong kondisyon ay madalas may history ng upper respiratory infection or intestinal disease, madalas magkasakit, hindi matagal magtrabaho, nasal congestion, headache, sore throat, cough, poor appetite, loose stool, bloating, abdominal pain, nausea, vomiting, dizziness, spontaneous sweating, pale complexion, pale tongue with thin white coating, weak pulse. Ang pangangasiwa ay dapat strengthen the spleen, tonify the lung, boost defense. Gamitin ang Zuan Yin Shengjing 2nd Formula (self-made): 15 grams each of astragalus, Chinese yam, white atractylodes, poria, codonopsis, coix seed; 10 grams each of chicken gizzard lining, angelica, dodder seed, polygonatum; 6 grams each of costus root (added later), schisandra berry; 3 grams of cardamom (added later). Inumin nang isang beses araw-araw.
Halimbawa 2: Li, lalaki, 33 taon. Unang pagbisita noong Mayo 10, 1993. 4 taon na walang anak, mag-asawa na, normal ang sex life, babae ay normal. Ang sperm test ay normal, serum ASAB (+), dati ay ginamit ang traditional and western medicine pero walang resulta. Kasalukuyang estado: chronic rhinitis at pharyngitis, madalas magkasakit, nasal congestion at sore throat, pale complexion. Red tongue with thin white coating, deep weak pulse. Ginamit ang Zuan Yin Shengjing 2nd Formula na may sedikit na pagbabago, inumin nang higit sa 3 buwan, ang mga sintomas ay bumaba, hindi na madaling magkasakit. Ang sperm test ay normal, serum ASAB ay negative. Ginamit ang original formula para sa 3 buwan, ang asawa ay nagbuntis at nagdalaw ng babae.
3. Alisin ang dampness, alisin ang heat toxin, clean the source. Ang mga inflammation sa reproductive system ng lalaki ay may mataas na rate ng positive ASAB sa serum at seminal plasma, na isa sa mga pangunahing dahilan ng immune reaction. Ang dahilan ay dahil sa sobra ng mataba at matamis na pagkain o sobra ng alak, na nakakasira sa spleen at stomach, na nagdudulot ng impaired digestion, o infection ng impure toxins, na nagdudulot ng dampness and heat toxin na sumasakop sa sperm chamber, na nagdudulot ng heat damage sa blood, at dampness and toxin na nakakasira sa sperm duct. Ang mga pasyente na may ganitong kondisyon ay madalas may history ng acute and chronic prostatitis, orchitis, epididymitis. Ang sintomas ay frequent urination, urgent urination, discomfort sa pag-ihi, or last drop of white discharge, feeling of incomplete voiding, dull pain in perineum, or heaviness, discomfort in testicles or epididymis, cloudy or yellow urine, red tongue with thin white coating and thick yellow root, string-like slippery pulse. Ang pangangasiwa ay dapat clear heat, promote diuresis, detoxify, and remove dampness. Gamitin ang Zuan Yin Shengjing 3rd Formula (self-made): 15 grams each of coix seed, poria; 10 grams each of salvia, plantain seed (wrapped), epimedium, white atractylodes, sand jujube seed, eucommia, ligusticum; 30 grams each of herba hedyotis, poria, motherwort; 6 grams each of calamus, phellodendron. Inumin nang isang beses araw-araw.
Halimbawa 3: Wang, lalaki, 32 taon. Unang pagbisita noong Abril 20, 1994. 2 taon na walang anak, mag-asawa na, normal ang sex life, babae ay normal. Ang sperm test ay normal, serum ASAB (+), seminal plasma ASAB (+). May history ng chronic prostatitis, last drop of white discharge, frequent and urgent urination, dull pain in perineum and pubic area, low back ache, dry mouth, sticky taste, yellow and hard stool. Pagsusuri: tender prostate, phospholipid bodies (++), pus cells (+++), pH 7.5. Red tongue, thick yellow root, string-like slippery pulse with slight rapidity. Pangangasiwa: remove dampness and heat toxin. Gamit ang Zuan Yin Shengjing 3rd Formula na may sedikit na pagbabago, inumin nang 4 buwan, ang lahat ng sintomas ay nawala. Prostate fluid test: phospholipid bodies (+++), few pus cells. Ginamit ang original method para sa 2 buwan, ang asawa ay nagbuntis at nagdalaw ng isang lalake.
4. Remove phlegm and blood stasis, open meridians, improve sperm passage. Ang sperm ay mahalaga sa pag-iimbak at pagpigil, ngunit kailangan rin ng appropriate release upang mapanatili ang normal na function ng sperm chamber. Kung ang lalaki ay sobra sa sweet and fatty foods, ang phlegm will be generated internally, o emotional injury causing qi stagnation, o injury due to fall, o chronic reproductive tract inflammation that persists, all these can lead to phlegm and blood stasis together, forming a mass, leading to blockage or obstruction of the sperm channel. If sperm cannot be released properly, new sperm cannot be produced, and if it flows backward into the blood, it can trigger the production of antibodies. According to Ye Tian-shi’s saying “For sperm stasis, first treat the dirty and rotten matter in the palace,” use methods to remove phlegm and blood stasis. These herbs can also reduce capillary permeability, decrease inflammatory exudate, promote absorption, improve weakened immune system function, and eliminate harmful immune reactions against self. Pasienteng may ganitong kondisyon ay madalas may history ng chronic reproductive tract inflammation or injury to tendons and muscles. Sintomas: discomfort in lower abdomen or genital area, low back pain, epididymal nodules, testicular tenderness, dark red tongue with purple hue, thin white coating, choppy pulse. Pangangasiwa: remove phlegm and blood stasis. Gamitin ang Zuan Yin Shengjing 4th Formula (self-made): 10 grams each of pinellia, fritillaria, scrophularia, white mustard seed, green tangerine peel, tangerine peel, cattail pollen (wrapped), salvia, non-dormant herb, angelica, ligusticum, pangolin scale (pre-boiled), seaweed, kelp; 30 grams of oyster shell (pre-boiled). Inumin nang isang beses araw-araw.
Halimbawa 4: Luo, lalaki, 30 taon. Unang pagbisita noong Mayo 12, 1993. 3 taon na walang anak, mag-asawa na, normal ang sex life, babae ay normal. Sperm count: 34 million/ml, motility: 50%, serum ASAB (+), iba pang normal. May constant sensation of scrotal heaviness, right epididymis occasionally painful, usually resolves by itself, easily triggered after fatigue, accompanied by low back pain and weakness, sticky mouth. Pagsusuri: slightly enlarged, smooth, firm, tender right epididymis head; thickened right vas deferens. Dark red tongue with purple hue, white root with greasy coating. Diagnosis: phlegm-dampness and blood stasis obstructing internally. Pangangasiwa: remove phlegm and blood stasis, clear dampness, disperse epididymal nodules. Gamit ang Zuan Yin Shengjing 4th Formula na may pagbabago, inumin nang 4 buwan, ang lahat ng sintomas ay nawala. Sperm test at serum ASAB ay pareho normal. Inirerekomenda ang original formula para sa pagpapatibay, at matapos ang follow-up, ang asawa ay nagdalaw ng babae.
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