Shengmai San 【Source】"Yixue Qiyuan" Vol. 2. 【Alternative Names】Shengmai Tang (in "Danxi Xinfa" Vol. 1). 【Composition】Mai Men Dong 1.5 grams, Wu Wei Zi 7 grains, Ren Shen 1.5 grams 【Usage】Decoct using flowing spring water, take at any time. 【Function】Tonify lung qi, nourish yin, generate fluids. 【Indication】Heat damage to qi and yin, fatigue, shortness of breath, weak speech, excessive sweating, thirst, dry throat and tongue, weak pulse; chronic cough due to lung deficiency with combined qi-yin injury, dry cough with little phlegm, shortness of breath, spontaneous sweating, weak pulse. Currently used for heatstroke, summer heat in children, functional low-grade fever, and other febrile diseases with qi-yin deficiency. Also used for heart failure, shock, and other critical conditions. 【Discussion】In this formula, Ren Shen tonifies lung qi and generates body fluids—primary herb; Mai Men Dong nourishes yin, clears lungs, and generates fluids—secondary herb; Wu Wei Zi astringes the lungs, stops thirst, and controls sweating—auxiliary herb. Together, they achieve the effect of tonifying the lungs, replenishing qi, nourishing yin, and generating fluids. 【Experimental Research】1. Trace Element Analysis: "Zhongchengyao Yanjiu" 1986(8):17. Using atomic absorption spectrophotometry, trace elements in Shengmai San were measured. Iron content was highest among the three herbs, especially Wu Wei Zi; manganese content was also highest in Wu Wei Zi; nickel was more abundant in Mai Men Dong; copper and chromium levels were also higher in Wu Wei Zi. 2. Enhancing Myocardial Tolerance to Hypoxia: "Zhonghua Yixue Zazhi" 1974(4):246. Experimental results via electrocardiography and histochemistry showed Shengmai San improves myocardial tolerance to hypoxia, enabling ischemic myocardium to function economically, prolonging survival time. This may be related to improved synthesis metabolism and ion transport systems in ischemic myocardium, reducing oxygen and energy consumption, thus giving this formula a special "cardiotonic effect" for cardiac resuscitation. 3. Improving Microcirculation: "Liaoning Zhongyi Zazhi" 1984(12):36. Shengmai injection improves experimental microcirculatory disorders caused by high-molecular dextran and blocks disseminated intravascular coagulation, providing experimental pharmacological basis for clinical treatment of coronary heart disease, angina pectoris, myocardial infarction, etc. |